anti-GPR44 Antibody

• Catalog number
  48-122
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells.
• Gene names
  PTGDR2, CD294, CRTH2, CD294 antigen, DP2, DL1R, G protein-coupled receptor 44, G-protein coupled receptor 44, HCRTH2, DP2 prostaglandin receptor, GPR44, Prostaglandin D2 receptor 2
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  BLAST analysis of the peptide immunogen showed no homology with other human proteins, except KCNN2 (50%).
• Antigen
  GPR44 antibody was made against a peptide located in the C-Terminal cytoplasmic domain of GPR44 (Human).
• Immuno application
  ELISA, immuno-histo-chemistry
• Antibody advice
  GPR44 antibody can be used in immunohistochemistry starting at 10 ug/mL.
• Suspention pH azide
  PBS, 0.1% sodium azide.
• Keep at
  GPR44 antibody should be stored long term (months) at -80 grades C and short term (days) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Gorilla, Human
• Omim nr
  296439334
• Ncbi nr
  Q9Y5Y4
• Vial with antibody
  in solution
• NCBI GENE nr
  11251
• GENE symbol
  PTGDR2
• Antigene name
  prostaglandin D2 receptor 2
• Source
  Homo sapiens
• Protein nr
  Q9Y5Y4
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GPR44  
• Gene symbol
  PTGDR2
• Short name
  anti-GPR44 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toGPR44 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4502
• Gene
  PTGDR2
• Long gene name
  prostaglandin D2 receptor 2
• Synonyms gene
  • GPR44
• Synonyms gene name
  • G protein-coupled receptor 44
• Synonyms
  • CRTH2
  • CD294
  • DP2
• Synonyms name
  • chemoattractant receptor homologous molecule expressed on T helper type 2 cells
• GenBank acession
  • AF118265
• Locus
  11q12.2
• Discovery year
  1999-03-12
• Entrez gene record
  11251
• Pubmed identfication
  • 10036181
• RefSeq identity
  • NM_004778
• Classification
  • CD molecules
  • Prostaglandin receptors
• VEGA ID
  OTTHUMG00000167796

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products