anti-GOLPH1 Antibody
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Catalog number5439
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoGOLPH1 Antibody: GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.
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Gene namesGOLPH1 Antibody: PAP7, GCP60, GOCAP1, GOLPH1, Golgi resident protein GCP60, Acyl-CoA-binding domain-containing protein 3
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Antibodie s labelunlabelled serum
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PurityGOLPH1 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenGOLPH1 antibody was made against a 16 amino acid synthetic peptide from near the amino terminus of human GOLPH1.
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Immuno applicationELISA, Western Blot
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Antibody adviceGOLPH1 antibody can be used for detection of GOLPH1 by Western blot at 1 - 2 ug/mL.
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Suspention pH azideGOLPH1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atGOLPH1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr119590181
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Ncbi nrEAW69775
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr64746
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GENE symbolACBD3
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Antigene nameacyl-Coenzyme A binding domain containing 3
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SourceHomo sapiens
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Protein nrQ9H3P7
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolACBD3
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Short nameanti-GOLPH1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toGOLPH1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameacyl-CoA binding domain containing 3
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Synonyms gene
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Synonyms gene name
- golgi complex associated protein 1, 60kDa
- acyl-Coenzyme A binding domain containing 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-04-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- A-kinase anchoring proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
