anti-Gle1 Antibody
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Catalog number4963
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoGle1 Antibody: The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.
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Gene namesGle1 Antibody: LCCS, GLE1L, LCCS1, hGLE1, Nucleoporin GLE1, GLE1-like protein
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Antibodie s labelunlabelled serum
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PurityGle1 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenGle1 antibody was made against a 15 amino acid synthetic peptide near the carboxy terminus of human Gle1.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceGle1 antibody can be used for detection of Gle1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 5 ug/mL.
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Suspention pH azideGle1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atGle1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr51317384
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Ncbi nrNP_001003722
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr2733
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GENE symbolGLE1
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Antigene nameGLE1 RNA export mediator homolog (yeast)
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SourceHomo sapiens
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Protein nrQ53GS7
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolGLE1
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Short nameanti-Gle1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toGle1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameGLE1 RNA export mediator
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Synonyms gene
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Synonyms gene name
- GLE1 (yeast homolog)-like, RNA export mediator
- GLE1 RNA export mediator-like (yeast)
- GLE1 RNA export mediator (yeast)
- lethal congenital contracture syndrome 1
- GLE1 RNA export mediator homolog (yeast)
- GLE1, RNA export mediator
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-06-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nucleoporins
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data