anti-GFR alpha 2 Antibody
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Catalog number1135
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Price:
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Size0.02 mg, 0.1 mg
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Gene infoGFR alpha 2 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRβ, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa;-2 recently. GFRa;-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa;-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
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Gene namesGFR alpha 2 Antibody: NTNRA, RETL2, TRNR2, GDNFRB, NRTNR-ALPHA, GDNF family receptor alpha-2, GDNF receptor beta, GDNF receptor alpha-2
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Antibodie s labelunlabelled serum
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PurityGFR alpha 2 Antibody is Antibody is DEAE purified.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenGFR alpha 2 antibody was made against a 15 amino acid peptide near the center of human GFR alpha 2.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry
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Antibody adviceGFR alpha 2 antibody can be used for detection of GFR alpha 2 by Western blot at 1 ug/mL. A 52 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 5 ug/mL.
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Suspention pH azideGFR alpha 2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atGFR alpha 2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr2145080
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Ncbi nrAAC52036
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KDa52 kDa
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Vial with antibodyin solution
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NCBI GENE nr2675
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GENE symbolGFRA2
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Antigene nameGDNF family receptor alpha 2
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SourceHomo sapiens
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Protein nrO00451
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DescriptionThe anti-GFR alpha 2 Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolRAPGEF5, GFRA1
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Short nameanti-GFR alpha 2 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toGFR a 2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 5
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Synonyms gene name
- Rap guanine nucleotide exchange factor (GEF) 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-03-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameGDNF family receptor alpha 1
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-01-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data