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Gene info
FRL1 Antibody: The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
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Gene names
FRL1 Antibody: FMNL, FHOD4, KW-13, C17orf1, C17orf1B, FMNL, Formin-like protein 1, CLL-associated antigen KW-13
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Antibodie s label
unlabelled serum
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Purity
FRL1 Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Spicific to
FRL1 antibody is human, mouse and rat reactive. Three alternatively spliced transcript variants have been observed
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Antigen
Rabbit polyclonal FRL1 antibody was made against a 16 amino acid peptide near the carboxy terminus of human FRL1.
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Immuno application
ELISA, Western Blot, immuno fluorescence
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Antibody advice
FRL1 antibody can be used for detection of FRL1 by Western blot at 1 - 2 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azide
FRL1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
FRL1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse, Rat
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Omim nr
33356148
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Ncbi nr
NP_005883
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KDa
121 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
752
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GENE symbol
FMNL1
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Antigene name
formin-like 1
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Source
homo sapiens
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Protein nr
O95466
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps