anti-ERGIC53 Monoclonal Antibody
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Catalog number
PM-7213
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Price
Please ask
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Size
0.02 mg, 0.1 mg
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Gene info
ERGIC53 Monoclonal Antibody: ERGIC53, also known as lectin mannose-binding 1 (LMAN1) protein is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
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Gene names
ERGIC53 Monoclonal Antibody: Lectin mannose-binding 1, LMAN1, endoplasmic reticulum-golgi intermediate compartment protein 53, ERGIC-53, F5F8D, FMFD1, MCFD1, MR60, gp58
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Antibodie s label
unlabelled serum
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Purity
ERGIC53 Monoclonal Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Monoclonal
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Immunoglobulin
IgG1
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Spicific to
At least two isoforms of ERGIC53 are known to exist.
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Antigen
Mouse monoclonal ERGIC53 antibody was made against a 19 amino acid peptide near the carboxy terminus of human ERGIC53.
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Immuno application
ELISA, Western Blot
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Antibody advice
ERGIC53 antibody can be used for detection of ERGIC53 by Western blot at 1 - 2 ug/mL.
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Suspention pH azide
ERGIC53 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
ERGIC53 Monoclonal antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works with
Human, Mouse
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Omim nr
5031873
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Ncbi nr
NP_005561
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KDa
Predicted: 56 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
3998
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GENE symbol
LMAN1
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Antigene name
lectin, mannose-binding, 1
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Source
homo sapiens
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps
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Gene target
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Gene symbol
LMAN1
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Short name
anti-ERGIC53 Monoclonal Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Alternative name
Antibody toERGIC53 monoclonal (antibody to-)
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Alternative technique
antibodies
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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