anti-EPM2A Antibody

  • Catalog number
    7023
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    EPM2A Antibody: The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
  • Gene names
    EPM2A Antibody: EPM2, MELF, Laforin, Lafora PTPase, LAFPTPase
  • Antibodie s label
    unlabelled serum
  • Purity
    EPM2A Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Spicific to
    At least four isoforms of EPM2A are known to exist; this antibody will detect all but the shortest isoform.
  • Antigen
    EPM2A antibody was made against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A.
  • Immuno application
    ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
  • Antibody advice
    EPM2A antibody can be used for detection of EPM2A by Western blot at 1 - 2 ug/mL.
  • Suspention pH azide
    EPM2A Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    EPM2A antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    11321613
  • Ncbi nr
    NP_005661
  • KDa
    36 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    7957
  • GENE symbol
    EPM2A
  • Antigene name
    epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
  • Source
    homo sapiens
  • Protein nr
    O95278
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    EPM2A  
  • Gene symbol
    EPM2A, EPM2A-DT
  • Short name
    anti-EPM2A Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toEPM2A (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    EPM2A glucan phosphatase, laforin
  • Synonyms gene name
    • epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
    • epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
    • EPM2A, laforin glucan phosphatase
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-10-01
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Atypical dual specificity phosphatases
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    EPM2A divergent transcript
  • Synonyms gene
  • Synonyms gene name
    • FBXO30 divergent transcript
  • Locus
  • Discovery year
    2020-01-17
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Divergent transcripts
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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