anti-DNM1L Antibody

• Catalog number
  7603
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  The Dynamin-1-like protein (DNM1L) is a member of the dynamin superfamily of GTPases (1). DNM1L mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis (2). Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) (3).
• Gene names
  DNM1L Antibody: DLP1, DRP1, DVLP, EMPF, DYMPLE, HDYNIV, DLP1, Dynamin-1-like protein, Dynamin family member proline-rich carboxyl-terminal domain less
• Antibodie s label
  unlabelled serum
• Purity
  DNM1L antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  DNM1L antibody is human and mouse reactive. At least four isoforms of DNM1L are known to exist; this antibody will detect the two longest isoforms.
• Antigen
  DNM1L antibody was made against a 19 amino acid peptide near the center of human DNM1L.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence
• Antibody advice
  DNM1L antibody can be used for detection of DNM1L by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunocytochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  DNM1L antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  DNM1L antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse
• Omim nr
  171460914
• Ncbi nr
  NP_036192
• KDa
  Predicted: 81 kDa Observed: 80 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  10059
• GENE symbol
  DNM1L
• Antigene name
  dynamin 1-like
• Source
  homo sapiens
• Protein nr
  O00429
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DNM1L  
• Gene symbol
  DNM1L
• Short name
  anti-DNM1L Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toDNM1L (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  dynamin 1-like, DLP1 and DRP1 and DVLP and DYMPLE and EMPF and HDYNIV, DNM1L and IDBG-26348 and ENSG00000087470 and 10059, protein homodimerization activity, Cell surfaces, Dnm1l and IDBG-136828 and ENSMUSG00000022789 and 74006, DNM1L and IDBG-638362 and ENSBTAG00000011395 and 540892

Gene info

• Identity
  HGNC:2973
• Gene
  DNM1L
• Long gene name
  dynamin 1 like
• Synonyms
  • DRP1
  • DVLP
  • HDYNIV
  • DYMPLE
  • VPS1
• GenBank acession
  • AF000430
• Locus
  12p11.21
• Discovery year
  2000-04-12
• Entrez gene record
  10059
• Pubmed identfication
  • 9348079
  • 9731200
• RefSeq identity
  • NM_012062
• VEGA ID
  OTTHUMG00000169451

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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