anti-DEDD2 Antibody

• Catalog number
  3071
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  DEDD2 Antibody: Apoptotic signals are often triggered by cell surface death receptors through protein-protein interactions mediated by conserved domains such as the death effector domain. A novel death effector domain (DED)-containing protein, DEDD2, has been recently identified and its over-expression in transfected cells induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas, TRAIL, and FADD. More recently, work has shown that DEDD2 can bind caspase-8 and -10 in addition to FLIP but not FADD. Like the related protein DEDD, DEDD2 translocates from the cytosol to the nucleus upon induction of apoptosis, and it has been suggested that DEDD2 may target caspase-8 to the nucleus and that DEDD2 thus plays a critical role in death receptor-induced apoptosis. At least two alternatively spliced transcript variants encoding distinct isoforms have been found for DEDD2.
• Gene names
  DEDD2 Antibody: FLAME-3, FLAME3, PSEC0004, DED-containing protein FLAME-3
• Antibodie s label
  unlabelled serum
• Purity
  DEDD2 Antibody is immunoaffinity chromatography purified IgG.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  DEDD2 antibody was made against a peptide corresponding to 11 amino acids near the amino-terminus of human DEDD2.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  DEDD2 antibody can be used for detection of DEDD2 by Western blot at 0.5 to 2 ug/mL.
• Suspention pH azide
  DEDD2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  DEDD2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  19923050
• Ncbi nr
  NP_579874
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  162989
• GENE symbol
  DEDD2
• Antigene name
  death effector domain containing 2
• Source
  Homo sapiens
• Protein nr
  Q8WXF8
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DEDD2  
• Gene symbol
  DEDD2
• Short name
  anti-DEDD2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toDEDD2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  death effector domain containing 2, DEDD2 and IDBG-53904 and ENSG00000160570 and 162989, receptor signaling complex scaffold activity, nuclei, Dedd2 and IDBG-156541 and ENSMUSG00000054499 and 67379, DEDD2 and IDBG-638613 and ENSBTAG00000005761 and 534251

Gene info

• Identity
  HGNC:24450
• Gene
  DEDD2
• Long gene name
  death effector domain containing 2
• Synonyms
  • FLAME-3
• GenBank acession
  • AY125488
• Locus
  19q13.2
• Discovery year
  2004-02-10
• Entrez gene record
  162989
• Pubmed identfication
  • 11965497
  • 12235123
• RefSeq identity
  • NM_133328
• Classification
  • Death effector domain containing
• VEGA ID
  OTTHUMG00000182763

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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