anti-DCLRE1C Antibody
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Catalog number26-583
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PricePlease ask
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Size50 ug
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Gene infoDCLRE1C is a nuclear protein that is involved in V (D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). This gene encodes a nuclear protein that is involved in V (D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).
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Gene namesDCLRE1C, A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCLRE1C.
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Immuno applicationELISA, Western Blot
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Antibody adviceDCLRE1C antibody can be used for detection of DCLRE1C by ELISA at 1:2500. DCLRE1C antibody can be used for detection of DCLRE1C by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store DCLRE1C antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman, Rat
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Omim nr76496499
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Ncbi nrNP_001029029
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KDa65 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr64421
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GENE symbolDCLRE1C
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Antigene nameDNA cross-link repair 1C
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SourceHomo sapiens
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Protein nrQ96SD1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDCLRE1C
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Short nameanti-DCLRE1C Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toDNA cross-link repair 1C (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetDNA cross-link repair 1C, DCLRE1C and IDBG-56338 and ENSG00000152457 and 64421, hydrolase activity, nuclei, Dclre1c and IDBG-133199 and ENSMUSG00000026648 and 227525, DCLRE1C and IDBG-638047 and ENSBTAG00000010220 and 517886
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Gene info
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Identity
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Gene
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Long gene nameDNA cross-link repair 1C
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Synonyms gene
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Synonyms gene name
- severe combined immunodeficiency, type a (Athabascan)
- DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-01-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DNA cross-link repair family
- MBL fold containing DNA/RNA interacting subfamily
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data