anti-CXCR4 Antibody

• Catalog number
  XW-7735
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  FUNCTION: Receptor for the C-X-C chemokine SDF-1. Transduces a signal by increasing the intracellular calcium ions level. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a primary receptor for some HIV-2 isolates and as a coreceptor with CD4 for HIV-1 X4 viruses (lymphocyte-tropic HIV-1 viruses, also called syncytium-inducing (SI) strains). Promotes Env-mediated fusion of the virus.
• Gene names
  C-X-C chemokine receptor type 4, FB22, CXC-R4, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LESTR, NPY3R, NPYRL, HSY3RR, NPYY3R, D2S201E, CXC chemokine receptor type 4, CXCR-4, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Fusin, Leukocyte-derived seven transmembrane domain receptor, CD184 antigen
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Purified
• Ab raised in
  Chicken
• Type
  Polyclonal
• Antigen
  6-41
• Immuno application
  Western Blot
• Antibody advice
  C-X-C chemokine receptor type 4 antibody can be used for the detection of C-X-C chemokine receptor type 4 by Western Blot.
• Suspention pH azide
  Phosphate-Buffered Saline. No preservatives added.
• Keep at
  CXCR4 antibody can be stored at 4 grades C for short term (weeks). Long term storage should be at -20 grades C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat, Bovine
• Omim nr
  4503175
• Ncbi nr
  NP_003458.1
• KDa
  39.7 kDa (calculated)
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  7852
• GENE symbol
  CXCR4
• Antigene name
  chemokine (C-X-C motif) receptor 4
• Source
  Homo sapiens
• Protein nr
  P61073
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CXCR4  
• Gene symbol
  CXCR4
• Short name
  anti-CXCR4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCXCR4 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-X-C motif) receptor 4, CD184 and D2S201E and FB22 and HM89 and HSY3RR and LAP-3 and LAP3 and LCR1 and LESTR and NPY3R and NPYR and NPYRL and NPYY3R and WHIM, CXCR4 and IDBG-71032 and ENSG00000121966 and 7852, ubiquitin binding, Cell surfaces, Cxcr4 and IDBG-189999 and ENSMUSG00000045382 and 12767, CXCR4 and IDBG-642187 and ENSBTAG00000001060 and 281736

Gene info

• Identity
  HGNC:2561
• Gene
  CXCR4
• Long gene name
  C-X-C motif chemokine receptor 4
• Synonyms gene name
  • chemokine (C-X-C motif), receptor 4 (fusin)
  • chemokine (C-X-C motif) receptor 4
• Synonyms
  • LESTR
  • NPY3R
  • HM89
  • NPYY3R
  • D2S201E
  • fusin
  • HSY3RR
  • NPYR
  • CD184
• GenBank acession
  • AF005058
• Locus
  2q22.1
• Discovery year
  1998-09-17
• Entrez gene record
  7852
• Pubmed identfication
  • 9599023
  • 9379028
• Classification
  • C-X-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000153583
• Locus Specific Databases
  • CXCR4base: Mutation registry for WHIM syndrome (warts, hypogammaglobulinemia, immunodeficiency, and myelokathexis)
  • LRG_51

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products