anti-CDCA8 Antibody

• Catalog number
  4751
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  CDCA8 Antibody: CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division. It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase. CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues. In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation. Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53. Its aberrant expression is linked to a poor prognosis for gastric cancer.
• Gene names
  CDCA8 Antibody: BOR, DasraB, MESRGP, BOREALIN, PESCRG3, Borealin, Cell division cycle-associated protein 8, hDasra-B
• Antibodie s label
  unlabelled serum
• Purity
  CDCA8 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  CDCA8 antibody was made against a 19 amino acid synthetic peptide near the amino terminus of the human CDCA8.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  CDCA8 antibody can be used for detection of CDCA8 by Western blot at 1 and 2 ug/mL. Antibody can also be used for immunoflourescence starting at 20 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  CDCA8 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  CDCA8 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  8922438
• Ncbi nr
  NP_060571
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  55143
• GENE symbol
  CDCA8
• Antigene name
  cell division cycle associated 8
• Source
  Homo sapiens
• Protein nr
  Q53HL2
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CDCA8  
• Gene symbol
  CDCA8
• Short name
  anti-CDCA8 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCDCA8 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14629
• Gene
  CDCA8
• Long gene name
  cell division cycle associated 8
• Synonyms
  • FLJ12042
  • MESRGP
  • BOR
  • DasraB
• Synonyms name
  • borealin
• GenBank acession
  • BG354581
• Locus
  1p34.3
• Discovery year
  2002-04-03
• Entrez gene record
  55143
• Pubmed identfication
  • 12188893
  • 15260989
• RefSeq identity
  • NM_018101
• Classification
  • Chromosomal passenger complex
• VEGA ID
  OTTHUMG00000004320

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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