anti-CD59 Antibody

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• Catalog number
  7235
• Price:

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• Size
  0.02 mg, 0.1 mg

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• Gene info
  CD59 Antibody: The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.
• Gene names
  CD59 Antibody: 1F5, EJ16, EJ30, EL32, G344, MIN1, MIN2, MIN3, MIRL, HRF20, MACIF, MEM43, MIC11, MSK21, 16.3A5, HRF-20, MAC-IP, p18-20, CD59 glycoprotein, 1F5 antigen
• Antibodie s label
  unlabelled serum
• Purity
  CD59 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  Rabbit polyclonal CD59 antibody was made against a 14 amino acid peptide near the amino terminus of human CD59.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  CD59 antibody can be used for detection of CD59 by Western blot at 1 - 2 ug/mL.
• Suspention pH azide
  CD59 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  CD59 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse
• Omim nr
  10835165
• Ncbi nr
  NP_000602
• KDa
  14 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  966
• GENE symbol
  CD59
• Antigene name
  CD59 molecule, complement regulatory protein
• Source
  homo sapiens
• Protein nr
  P13987
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

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• Gene target
  CD59  
• Gene symbol
  CD59
• Short name
  anti-CD59 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCD59 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  CD59 molecule, complement regulatory protein, 16.3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 and IDBG-38813 and ENSG00000085063 and 966, protein binding, Extracellular, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574

Gene info

• Identity
  HGNC:1689
• Gene
  CD59
• Long gene name
  CD59 molecule (CD59 blood group)
• Synonyms gene
  • MIC11
  • MIN1
  • MSK21
  • MIN2
  • MIN3
• Synonyms gene name
  • CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
  • CD59 antigen, complement regulatory protein
  • CD59 molecule, complement regulatory protein
  • CD59 molecule
• Synonyms
  • 16.3A5
  • EJ16
  • EJ30
  • EL32
  • G344
  • p18-20
• Locus
  11p13
• Discovery year
  1989-06-30
• Entrez gene record
  966
• Pubmed identfication
  • 7691713
  • 27187193
• RefSeq identity
  • NM_203329
• Classification
  • Blood group antigens
  • Complement system regulators and receptors
  • CD molecules
  • LY6/PLAUR domain containing
• VEGA ID
  OTTHUMG00000166270
• Locus Specific Databases
  • CD59base: Mutation registry for CD59 deficiency
  • LRG_41

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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