anti-CD59 Antibody
#
-
Catalog number7235
-
Price:
-
Size0.02 mg, 0.1 mg
-
-
Gene infoCD59 Antibody: The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.
-
Gene namesCD59 Antibody: 1F5, EJ16, EJ30, EL32, G344, MIN1, MIN2, MIN3, MIRL, HRF20, MACIF, MEM43, MIC11, MSK21, 16.3A5, HRF-20, MAC-IP, p18-20, CD59 glycoprotein, 1F5 antigen
-
Antibodie s labelunlabelled serum
-
PurityCD59 Antibody is affinity chromatography purified via peptide column.
-
Ab raised inRabbit
-
TypePolyclonal
-
ImmunoglobulinIgG
-
AntigenRabbit polyclonal CD59 antibody was made against a 14 amino acid peptide near the amino terminus of human CD59.
-
Immuno applicationELISA, Western Blot
-
Antibody adviceCD59 antibody can be used for detection of CD59 by Western blot at 1 - 2 ug/mL.
-
Suspention pH azideCD59 Antibody is supplied in PBS containing 0.02% sodium azide.
-
Keep atCD59 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
-
Works withHuman, Mouse
-
Omim nr10835165
-
Ncbi nrNP_000602
-
KDa14 kDa
-
Vial with antibodyin solution
-
Quantity per ml1 mg/mL
-
NCBI GENE nr966
-
GENE symbolCD59
-
Antigene nameCD59 molecule, complement regulatory protein
-
Sourcehomo sapiens
-
Protein nrP13987
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCD59
-
Short nameanti-CD59 Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toCD59 (antibody to-)
-
Alternative techniqueantibodies
-
Alternative to gene targetCD59 molecule, complement regulatory protein, 16.3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 and IDBG-38813 and ENSG00000085063 and 966, protein binding, Extracellular, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574
-
Gene info
-
Identity
-
Gene
-
Long gene nameCD59 molecule (CD59 blood group)
-
Synonyms gene
-
Synonyms gene name
- CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
- CD59 antigen, complement regulatory protein
- CD59 molecule, complement regulatory protein
- CD59 molecule
-
Synonyms
-
Locus
-
Discovery year1989-06-30
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Blood group antigens
- Complement system regulators and receptors
- CD molecules
- LY6/PLAUR domain containing
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data