anti-CCR3 Antibody

  • Catalog number
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    CCR3 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS. High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results indicate CCR3 plays an important role in HIV infection of CNS.
  • Gene names
    CCR3 Antibody: CKR3, CD193, CMKBR3, CC-CKR-3, C-C chemokine receptor type 3, Eosinophil eotaxin receptor, C-C CKR-3
  • Antibodie s label
    unlabelled serum
  • Purity
    CCR3 Antibody is immunoaffinity purified IgG.
  • Ab raised in
  • Type
  • Immunoglobulin
  • Antigen
    CCR3 antibody was made against a 14 amino acid synthetic peptide from near the amino terminus of human CCR3.
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    CCR3 antibody can be used for the detection of CCR3 by Western blot at 1 - 2 ug/mL.
  • Suspention pH azide
    CCR3 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    CCR3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
  • Ncbi nr
  • Vial with antibody
    in solution
  • NCBI GENE nr
  • GENE symbol
  • Antigene name
    chemokine (C-C motif) receptor 3
  • Source
    Homo sapiens
  • Protein nr
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
  • Gene target
  • Gene symbol
  • Short name
    anti-CCR3 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toCCR3 (antibody to-)
  • Alternative technique
  • Alternative to gene target
    chemokine (C-C motif) receptor 3, CC-CKR-3 and CD193 and CKR3 and CMKBR3, CCR3 and IDBG-30125 and ENSG00000183625 and 1232, C-C chemokine receptor activity, Plasma membranes, Ccr3 and IDBG-206550 and ENSMUSG00000035448 and 12771, BT.28967 and IDBG-647811 and ENSBTAG00000001338 and 408018
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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