anti-BFAR Antibody
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Catalog number5591
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Price:
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Size0.02 mg, 0.1 mg
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Gene infoBFAR Antibody: The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
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Gene namesBFAR Antibody: BAR, RNF47, BAR, Bifunctional apoptosis regulator, RING finger protein 47
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Antibodie s labelunlabelled serum
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PurityBFAR Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenBFAR antibody was made against a 14 amino acid synthetic peptide near the carboxy terminus of human BFAR.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceBFAR antibody can be used for detection of BFAR by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideBFAR Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atBFAR antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr7706091
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Ncbi nrNP_057645
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr51283
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GENE symbolBFAR
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Antigene namebifunctional apoptosis regulator
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SourceHomo sapiens
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Protein nrQ9NZS9
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBFAR
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Short nameanti-BFAR Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toBFAR (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetbifunctional apoptosis regulator, BFAR and IDBG-15415 and ENSG00000103429 and 51283, metal ion binding, Plasma membranes, Bfar and IDBG-133938 and ENSMUSG00000022684 and 67118, BFAR and IDBG-637140 and ENSBTAG00000021521 and 504902
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Gene info
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Identity
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Gene
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Long gene namebifunctional apoptosis regulator
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sterile alpha motif domain containing
- Ring finger proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data