anti-Beta-Catenin (phospho Ser33 / Ser37)Antibody

• Catalog number
  50-229
• Price
  Please ask
• Size
  0.1 mL

• Gene info
  Beta-catenin is a central component of the cadherin cell adhesion complex and plays an essential role in neural development in the Wingless/Wnt signaling pathway (Ding and Dale, 2002; Polakis, 2000). The role of beta-catenin in these processes is thought regulated by the sequential phosphorylation of Ser29 Ser33, Ser37 and Thr41 by glycogen synthase kinase 3beta (GSK3beta) (Liu et al., 2002). This hyperphosphorylation promotes the ubiquitylation and targeted destruction of beta-catenin. Mutations in components of this phosphorylation regulated process that prevent beta-catenin hyperphosphorylation by GSK3beta are strongly associated with cancers (Wang et al., 2003; Polakis, 2000; Liu et al., 2002).
• Gene names
  CTNNB, MRD19, armadillo, CTNNBORF Names:OK/SW-cl.35, PRO2286, Beta-catenin,
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Purified
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33, 37 of human beta-catenin.
• Immuno application
  Western Blot
• Antibody advice
  The antibody has been directly tested for reactivity in Western blots with human tissue. It is anticipated that the antibody will react with mouse, rat and Xenopus based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
• Suspention pH azide
  100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
• Keep at
  Beta-Catenin antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
• Works with
  Human, Mouse, Rat, Xenopus
• Omim nr
  461854
• Ncbi nr
  P35222
• KDa
  83
• Vial with antibody
  in solution
• NCBI GENE nr
  1499
• GENE symbol
  CTNNB1
• Antigene name
  catenin (cadherin-associated protein), beta 1, 88kDa
• Source
  Homo sapiens
• Protein nr
  P35222
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Beta-Catenin   phospho   Ser33   Ser37  
• Short name
  anti-Beta-Catenin (phospho Ser33 / Ser37)Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toBeta-Catenin (phosphorilated Ser33 / Ser37)(antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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