anti-BCL2A1 Antibody
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Catalog number31-083
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PricePlease ask
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Size50 ug
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Gene infoBCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
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Gene namesBCL2A1, GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5
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Antibodie s labelunlabelled serum
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PurityAntibody is purified by peptide affinity chromatography method.
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Ab raised inRabbit
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TypePolyclonal
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AntigenAntibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCL2A1.
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Immuno applicationELISA, Western Blot
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Antibody adviceBCL2A1 antibody can be used for detection of BCL2A1 by ELISA at 1:12500. BCL2A1 antibody can be used for detection of BCL2A1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azideAntibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep atFor short periods of storage (days) store at 4 grades C. For longer periods of storage, store BCL2A1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works withHuman
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Omim nr4757840
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Ncbi nrNP_004040
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KDa20 kDa
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Vial with antibodyLyophilized
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Quantity per ml1 mg/ml
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NCBI GENE nr597
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GENE symbolBCL2A1
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Antigene nameBCL2-related protein A1
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SourceHomo sapiens
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Protein nrQ16548
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBCL2A1
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Short nameanti-BCL2A1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toBCL2-related protein A1 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetBCL2-related protein A1, ACC-1 and ACC-2 and BCL2L5 and BFL1 and GRS and HBPA1, BCL2A1 and IDBG-25591 and ENSG00000140379 and 597, BH domain binding, Cytoplasm, BCL2A1 and IDBG-630216 and ENSBTAG00000000735 and 282151
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Gene info
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Identity
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Gene
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Long gene nameBCL2 related protein A1
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Synonyms gene
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Synonyms
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Locus
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Discovery year1995-05-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Minor histocompatibility antigens
- BCL2 family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data