anti-BAD (phospho Ser112) Antibody

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• Catalog number
  79-134
• Price:

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• Size
  0.1 mg

# #

• Gene info
  The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
• Gene names
  BBC2, BCL2L8, ERBB, ERBB1, HER1, BBC6
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of BAD only when phosphorylated at serine 112.
• Antigen
  BAD (Phospho-Ser112) antibody was made against a peptide sequence around phosphorylation site of serine 112 (H-S-S (p) -Y-P) derived from Human BAD.
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  10835069
• Ncbi nr
  NP_004313.1
• KDa
  23 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  572
• GENE symbol
  BAD
• Antigene name
  BCL2-associated agonist of cell death
• Source
  Homo sapiens
• Protein nr
  Q92934
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

#

• Gene target
  BAD   phospho   Ser112  
• Gene symbol
  BAD, LAMP5
• Short name
  anti-BAD (phospho Ser112) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toBAD (phosphorilated Ser112) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2-associated a this GO nist of cell death, BBC2 and BCL2L8, BAD and IDBG-53423 and ENSG00000002330 and 572, protein heterodimerization activity, Cytoplasm, Bad and IDBG-137335 and ENSMUSG00000024959 and 12015, BT.55802 and IDBG-643918 and ENSBTAG00000012511 and 615013

Gene info

• Identity
  HGNC:936
• Gene
  BAD
• Long gene name
  BCL2 associated agonist of cell death
• Synonyms
  • BCL2L8
  • BBC2
• GenBank acession
  • AF021792
• Locus
  11q13.1
• Discovery year
  1997-10-16
• Entrez gene record
  572
• Pubmed identfication
  • 8929532
• RefSeq identity
  • NM_032989
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000134302

Gene info

• Identity
  HGNC:16097
• Gene
  LAMP5
• Long gene name
  lysosomal associated membrane protein family member 5
• Synonyms gene
  • C20orf103
• Synonyms gene name
  • chromosome 20 open reading frame 103
  • lysosomal-associated membrane protein family, member 5
• Synonyms
  • dJ1119D9.3
  • BAD-LAMP
  • UNC-46
• Synonyms name
  • brain and dendritic cell associated LAMP
• GenBank acession
  • AL121740
• Locus
  20p12.2
• Discovery year
  2001-07-17
• Entrez gene record
  24141
• Pubmed identfication
  • 11780052
  • 21642595
• RefSeq identity
  • NM_012261
• Classification
  • Lysosome associated membrane proteins
• VEGA ID
  OTTHUMG00000031851

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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