anti-ASC Antibody

• Catalog number
  2287
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  ASC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4). Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.
• Gene names
  ASC Antibody: ASC, TMS, TMS1, CARD5, TMS-1, ASC, Apoptosis-associated speck-like protein containing a CARD, Caspase recruitment domain-containing protein 5, hASC
• Antibodie s label
  unlabelled serum
• Purity
  ASC Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  ASC antibody was made against a 14 amino acid peptide near the carboxy terminus of human ASC .
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry
• Antibody advice
  ASC antibody can be used for detection of ASC/TMS1 by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 5 ug/mL.
• Suspention pH azide
  ASC Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  ASC antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  10801602
• Ncbi nr
  BAA87339
• KDa
  25 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  29108
• GENE symbol
  PYCARD
• Antigene name
  PYD and CARD domain containing
• Source
  Homo sapiens
• Protein nr
  Q9ULZ3
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ASC  
• Gene symbol
  SLC7A10, TRIP4, PYCARD
• Short name
  anti-ASC Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toASC (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11058
• Gene
  SLC7A10
• Long gene name
  solute carrier family 7 member 10
• Synonyms gene name
  • solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
• Synonyms
  • asc-1
• GenBank acession
  • AB037670
• Locus
  19q13.11
• Discovery year
  2000-06-02
• Entrez gene record
  56301
• Pubmed identfication
  • 10734121
  • 10863037
• RefSeq identity
  • NM_019849
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000180344

Gene info

• Identity
  HGNC:12310
• Gene
  TRIP4
• Long gene name
  thyroid hormone receptor interactor 4
• Synonyms
  • HsT17391
  • ZC2HC5
  • ASC-1
• Synonyms name
  • zinc finger, C2HC5-type
  • Activating Signal Cointegrator-1
• GenBank acession
  • L40371
• Locus
  15q22.31
• Discovery year
  1999-03-19
• Entrez gene record
  9325
• Pubmed identfication
  • 7776974
  • 12077347
• RefSeq identity
  • NM_016213
• Classification
  • Activating signal cointegrator 1 complex
  • Zinc fingers
• VEGA ID
  OTTHUMG00000133033

Gene info

• Identity
  HGNC:16608
• Gene
  PYCARD
• Long gene name
  PYD and CARD domain containing
• Synonyms
  • TMS-1
  • CARD5
  • ASC
• Synonyms name
  • apoptosis-associated speck-like
  • apoptosis-associated speck-like protein containing a CARD
• GenBank acession
  • AB023416
• Locus
  16p11.2
• Discovery year
  2004-06-25
• Entrez gene record
  29108
• Pubmed identfication
  • 11250163
  • 10567338
  • 11103776
• RefSeq identity
  • NM_013258
• Classification
  • Pyrin domain containing
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000176753

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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