anti-Apoa5(ab) Antibody [1G5G9(c)]
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Catalog number
32-109
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Price
Please ask
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Size
0.1 mg
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Gene info
Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
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Gene names
RAP3, UNQ411/PRO773, Apolipoprotein A5, Apo-AV, RAP3, APOAV
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Antibodie s label
unlabelled serum
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Ab raised in
Mouse
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Type
Monoclonal
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Monoclonal
1G5G9(c)
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Immunoglobulin
IgG1
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Antigen
Ni-NTA purified recombinant human APOA5 expressed in E. Coli strain BL21 (DE3).
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Immuno application
ELISA, Western Blot
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Antibody advice
Western Blot, ELISA.Dilution:Western Blot:1:2000 - 1:5,000ELISA:Determining optimal working dilutions by titration test.
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Suspention pH azide
Purified antibody in PBS containing 0.03% sodium azide.
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Keep at
Apoa5(ab) monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human
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Omim nr
60391728
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Ncbi nr
Q6Q788
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NCBI GENE nr
116519
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GENE symbol
APOA5
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Antigene name
apolipoprotein A-V
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Source
Homo sapiens
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Protein nr
Q6Q788
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Short name
anti-Apoa5(ab) Antibody [1G5G9(c)]
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toApoa5(Antibody) (antibody to-) [1G5G9(c)]
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Alternative technique
antibodies
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Alternative to gene target
apolipoprotein A-V, APOA5 and IDBG-72432 and ENSG00000110243 and 116519, lipoprotein particle receptor binding, Extracellular, Apoa5 and IDBG-161348 and ENSMUSG00000032079 and 66113, APOA5 and IDBG-630769 and ENSBTAG00000019764 and 538914
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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