anti-APBA2 Antibody

  • Catalog number
    6039
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    APBA2 Antibody: APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
  • Gene names
    APBA2 Antibody: X11L, MINT2, LIN-10, HsT16821, X11-BETA, D15S1518E, MGC:14091, X11L, Amyloid beta A4 precursor protein-binding family A member 2, Adapter protein X11beta, Mint-2
  • Antibodie s label
    unlabelled serum
  • Purity
    APBA2 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    APBA2 antibody was made against an 18 amino acid synthetic peptide near the center of human APBA2.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
  • Antibody advice
    APBA2 antibody can be used for detection of APBA2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
  • Suspention pH azide
    APBA2 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    APBA2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    22035550
  • Ncbi nr
    NP_005494
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    321
  • GENE symbol
    APBA2
  • Antigene name
    amyloid beta (A4) precursor protein-binding, family A, member 2
  • Source
    Homo sapiens
  • Protein nr
    Q99767
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    APBA2  
  • Gene symbol
    APBA2
  • Short name
    anti-APBA2 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toAPBA2 (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    amyloid beta precursor protein binding family A member 2
  • Synonyms gene
  • Synonyms gene name
    • X11-like
    • amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)
    • amyloid beta (A4) precursor protein-binding, family A, member 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1997-06-25
  • Entrez gene record
    321
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • PDZ domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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