anti-APBA2 Antibody
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Catalog number6039
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoAPBA2 Antibody: APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
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Gene namesAPBA2 Antibody: X11L, MINT2, LIN-10, HsT16821, X11-BETA, D15S1518E, MGC:14091, X11L, Amyloid beta A4 precursor protein-binding family A member 2, Adapter protein X11beta, Mint-2
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Antibodie s labelunlabelled serum
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PurityAPBA2 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenAPBA2 antibody was made against an 18 amino acid synthetic peptide near the center of human APBA2.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceAPBA2 antibody can be used for detection of APBA2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideAPBA2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atAPBA2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr22035550
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Ncbi nrNP_005494
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr321
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GENE symbolAPBA2
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Antigene nameamyloid beta (A4) precursor protein-binding, family A, member 2
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SourceHomo sapiens
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Protein nrQ99767
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolAPBA2
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Short nameanti-APBA2 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toAPBA2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameamyloid beta precursor protein binding family A member 2
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Synonyms gene
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Synonyms gene name
- X11-like
- amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)
- amyloid beta (A4) precursor protein-binding, family A, member 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data