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Gene info
APBA1 Antibody: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Aβ peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation.
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Gene names
APBA1 Antibody: X11, X11A, LIN10, MINT1, D9S411E, X11ALPHA, X11, Amyloid beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Mint-1
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Antibodie s label
unlabelled serum
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Purity
APBA1 Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Spicific to
At least two alternatively spliced isoforms are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other APBA proteins.
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Antigen
APBA1 antibody was made against a 19 amino acid synthetic peptide near the amino terminus of human APBA1.
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Immuno application
ELISA, Western Blot, immuno fluorescence
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Antibody advice
APBA1 antibody can be used for detection of APBA1 by Western blot at 0.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azide
APBA1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
APBA1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Human, Mouse, Rat
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Omim nr
22035548
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Ncbi nr
NP_001154
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KDa
92 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
320
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GENE symbol
APBA1
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Antigene name
amyloid beta A4 precursor protein-binding family A member 1
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Source
homo sapiens
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Protein nr
Q02410
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
APBA1
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Short name
anti-APBA1 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toAPBA1 (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
amyloid beta (A4) precursor protein-binding, family A, member 1, D9S411E and LIN10 and MINT1 and X11 and X11A and X11ALPHA, APBA1 and IDBG-69588 and ENSG00000107282 and 320, phosphatidylinositol-4, nuclei, Apba1 and IDBG-154300 and ENSMUSG00000024897 and 319924, APBA1 and IDBG-631959 and ENSBTAG00000008877 and 515571
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