anti-Apaf-1 Antibody [2E10]

• Catalog number
  PM-2015
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Apaf-1 Monoclonal Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. The mammalian homologous of the key cell death gene CED-4 in C. elegans was identified recently from human and mouse and designated Apaf1 for apoptosis protease-activating factor 1. Apaf1 binds to cytochrome c (Apaf2) and caspase-9 (Apaf3), which leads to caspase-9 activation. Activated caspase-9 in turn cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. Apaf1 transcript is ubiquitously expressed in human tissues.
• Gene names
  Apaf-1 Antibody [2E10] : CED4, APAF-1
• Antibodie s label
  unlabelled serum
• Purity
  Apaf-1 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  2E10
• Antigen
  A peptide corresponding to amino acids near the carboxy terminus of human Apaf1.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  Apaf1 antibody can be used for detection of Apaf1 by Western blot at 0.25 - 0.5 mg/mL. A 130 kDa band should be detected. Antibody can also be used for immunohistochemistry starting at 0.5 ug/mL.
• Suspention pH azide
  Apaf-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Apaf-1 monoclonal antibody can be stored at -20 grades C, stable for one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  2330015
• Ncbi nr
  AAC51678
• KDa
  130 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  317
• GENE symbol
  APAF1
• Antigene name
  apoptotic peptidase activating factor 1
• Source
  Homo sapiens
• Protein nr
  O14727
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Apaf-1   [2E10]  
• Short name
  anti-Apaf-1 Antibody [2E10]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toApaf-1 (antibody to-) [2E10]
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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