anti-Anthrax Protective Antigen Antibody
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Catalog number
3413
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Price
Please ask
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Size
0.02 mg, 0.1 mg
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Gene info
Anthrax Protective Antigen Antibody: Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism.
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Gene names
Anthrax Protective Antigen Antibody: pag, pXO1-110, BXA0164, GBAA_pXO1_0164, Protective antigen, Anthrax toxins translocating protein, PA
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Antibodie s label
unlabelled serum
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Purity
Anthrax Protective Antigen Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Antigen
Anthrax protective antigen antibody was made against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Anthrax protective antigen protein.
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Immuno application
ELISA
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Antibody advice
Anthrax protective antigen antibody can be used for the detection of Anthrax protective antigen protein in ELISA. It will detect 10 ng of free peptide at 1 ug/mL.
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Suspention pH azide
Anthrax Protective Antigen Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
Anthrax Protective Antigen antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Bacteria
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Omim nr
9280533
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Ncbi nr
AAF86457
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
3361714
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GENE symbol
pxo1_110
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Antigene name
Protective antigen
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Source
Bacillus anthracis
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Protein nr
P13423
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Antigens are peptides or recombinant or native dependent on the production method.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Short name
anti-Anthrax Protective Antigen Antibody
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Technique
Antibody, antigen, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antigenes
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Alternative name
Antibody toAnthrax Protective protein (antibody to-)
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Alternative technique
antibodies, antigenes
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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