anti-ADAMTS4 Antibody

• Catalog number
  48-124
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease.
• Gene names
  ADAMTS4, ADAMTS-2, ADAMTS-4, ADAM-TS 4, ADAM-TS4, ADMP-1, Aggrecanase-1, KIAA0688
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Antigen
  ADAMTS4 antibody was made against a peptide located in the C-Terminal domain of ADAMTS4 (Human).
• Immuno application
  immuno-histo-chemistry
• Antibody advice
  ADAMTS4 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 ug/mL, and immunofluorescence starting at 10 ug/mL.
• Suspention pH azide
  PBS, 0.1% sodium azide.
• Keep at
  Store ADAMTS4 antibody at 4 grades C for short term applications. For long term storage, aliquot and -20 grades C.
• Works with
  Gibbon, Dog, Horse, Human, Orangutan
• Omim nr
  317373445
• Ncbi nr
  O75173
• Vial with antibody
  in solution
• NCBI GENE nr
  9507
• GENE symbol
  ADAMTS4
• Antigene name
  ADAM metallopeptidase with thrombospondin type 1 motif, 4
• Source
  Homo sapiens
• Protein nr
  O75173
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ADAMTS4  
• Gene symbol
  ADAMTS4
• Short name
  anti-ADAMTS4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toADAMTS4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:220
• Gene
  ADAMTS4
• Long gene name
  ADAM metallopeptidase with thrombospondin type 1 motif 4
• Synonyms gene name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4
• Synonyms
  • KIAA0688
  • ADAMTS-2
  • ADMP-1
• GenBank acession
  • AB014588
• Locus
  1q23.3
• Discovery year
  1999-04-15
• Entrez gene record
  9507
• Pubmed identfication
  • 10094461
• RefSeq identity
  • NM_005099
• Classification
  • ADAM metallopeptidases with thrombospondin type 1 motif
• VEGA ID
  OTTHUMG00000034349

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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