PD-1/PD-L1 Blockade Bioassay, Propagation Model

• Catalog number
  J1252
• Price
  Please ask
• Size
  1 each

• Ambiant Carboglace
  Dry Ice

• Gene target
  PD-1/PD-L1   Blockade   Bioassay   Propagation   Model  
• Gene symbol
  PDCD1, CD274, ENPP2, ENPP3, PDCD1LG2, VSIR, SNCA, SPATA2, MTA2, MICALL1
• Short name
  PD-1/PD-L1 Blockade Bioassay, Propagation Model
• Technique
  Bioassay
• Alternative name
  PD-1/PD-L1 Blockade Bioassay, Propagation Model

Gene info

• Identity
  HGNC:8760
• Gene
  PDCD1
• Long gene name
  programmed cell death 1
• Synonyms gene
  • SLEB2
• Synonyms gene name
  • systemic lupus erythematosus susceptibility 2
• Synonyms
  • CD279
  • PD1
  • hSLE1
  • PD-1
• GenBank acession
  • AY206416
• Locus
  2q37.3
• Discovery year
  1994-05-24
• Entrez gene record
  5133
• Pubmed identfication
  • 7851902
  • 12402038
• RefSeq identity
  • NM_005018
• Classification
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000151342

Gene info

• Identity
  HGNC:17635
• Gene
  CD274
• Long gene name
  CD274 molecule
• Synonyms gene
  • PDCD1LG1
• Synonyms gene name
  • programmed cell death 1 ligand 1
  • CD274 antigen
• Synonyms
  • B7-H
  • B7H1
  • PD-L1
  • PDL1
  • B7-H1
• Synonyms name
  • B7 homolog 1
• GenBank acession
  • AF177937
• Locus
  9p24.1
• Discovery year
  2003-11-13
• Entrez gene record
  29126
• Pubmed identfication
  • 11015443
  • 10581077
• RefSeq identity
  • NM_014143
• Classification
  • Receptor ligands
  • C2-set domain containing
  • V-set domain containing
  • B7 family
  • CD molecules
• VEGA ID
  OTTHUMG00000019503

Gene info

• Identity
  HGNC:3357
• Gene
  ENPP2
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 2
• Synonyms gene
  • PDNP2
• Synonyms
  • ATX
  • PD-IALPHA
• Synonyms name
  • autotaxin
• GenBank acession
  • D45421
• Locus
  8q24.12
• Discovery year
  1995-08-10
• Entrez gene record
  5168
• Pubmed identfication
  • 8586446
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
• VEGA ID
  OTTHUMG00000164995

Gene info

• Identity
  HGNC:3358
• Gene
  ENPP3
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 3
• Synonyms gene
  • PDNP3
• Synonyms
  • PD-IBETA
  • gp130RB13-6
  • B10
  • CD203c
• GenBank acession
  • AF005632
• Locus
  6q23.2
• Discovery year
  1995-08-10
• Entrez gene record
  5169
• Pubmed identfication
  • 9344668
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
  • CD molecules
• VEGA ID
  OTTHUMG00000016292

Gene info

• Identity
  HGNC:18731
• Gene
  PDCD1LG2
• Long gene name
  programmed cell death 1 ligand 2
• Synonyms
  • PD-L2
  • Btdc
  • PDL2
  • bA574F11.2
  • CD273
  • B7-DC
• Synonyms name
  • B7 dendritic cell molecule
• GenBank acession
  • AF344424
• Locus
  9p24.1
• Discovery year
  2003-11-14
• Entrez gene record
  80380
• Pubmed identfication
  • 11224527
• RefSeq identity
  • NM_025239
• Classification
  • B7 family
  • CD molecules
  • Immunoglobulin like domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000019504

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

Gene info

• Identity
  HGNC:11138
• Gene
  SNCA
• Long gene name
  synuclein alpha
• Synonyms gene
  • PARK1
  • PARK4
• Synonyms gene name
  • Parkinson disease (autosomal dominant, Lewy body) 4
  • synuclein, alpha (non A4 component of amyloid precursor)
• Synonyms
  • NACP
  • PD1
• Synonyms name
  • non A4 component of amyloid precursor
  • alpha-synuclein
  • α-synuclein
• GenBank acession
  • L08850
• Locus
  4q22.1
• Discovery year
  1995-01-24
• Entrez gene record
  6622
• Pubmed identfication
  • 8248242
  • 14593171
• VEGA ID
  OTTHUMG00000130948
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:14681
• Gene
  SPATA2
• Long gene name
  spermatogenesis associated 2
• Synonyms
  • KIAA0757
  • PD1
  • tamo
  • PPP1R145
• Synonyms name
  • protein phosphatase 1, regulatory subunit 145
• GenBank acession
  • AB018300
• Locus
  20q13.13
• Discovery year
  2001-03-15
• Entrez gene record
  9825
• RefSeq identity
  • NM_006038
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000032704

Gene info

• Identity
  HGNC:7411
• Gene
  MTA2
• Long gene name
  metastasis associated 1 family member 2
• Synonyms gene
  • MTA1L1
• Synonyms gene name
  • metastasis associated gene family, member 2
• Synonyms
  • MTA1-L1
• GenBank acession
  • AB016591
• Locus
  11q12.3
• Discovery year
  1999-05-17
• Entrez gene record
  9219
• Pubmed identfication
  • 9929979
• RefSeq identity
  • NM_004739
• Classification
  • GATA zinc finger domain containing
  • NuRD complex subunits
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000167684

Gene info

• Identity
  HGNC:29804
• Gene
  MICALL1
• Long gene name
  MICAL like 1
• Synonyms gene name
  • MICAL-like 1
• Synonyms
  • MIRAB13
  • KIAA1668
  • MICAL-L1
• Synonyms name
  • molecule interacting with Rab13
• GenBank acession
  • BK000466
• Locus
  22q13.1
• Discovery year
  2006-11-24
• Entrez gene record
  85377
• Pubmed identfication
  • 11258795
  • 12110185
• RefSeq identity
  • NM_033386
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000150670

MeSH Data

• Name
  Models, Animal
• Concept
  Scope note: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.
• Tree numbers
  • E05.598

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