LDC000067

• Description:

  LDC000067 is a highly specific CDK9 inhibitor with an IC50 value of 44±10 nM in vitro.

• Product Name Alternative:

  LDC067

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Apoptosis; CDK

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/LDC000067.html

• Purity:

  99.00

• Solubility:

  DMSO : ≥ 47 mg/mL

• Smiles:

  O=S(CC1=CC=CC(NC2=NC=NC(C3=CC=CC=C3OC)=C2)=C1)(N)=O

• Molecular Formula:

  C18H18N4O3S

• Molecular Weight:

  370.43

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Albert TK, et al. Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor. Br J Pharmacol. 2014 Jan;171 (1) :55-68.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CDK1; CDK2; CDK4; CDK9

• CAS Number:

  [1073485-20-7]