LDC000067

• Description :

  LDC000067 is a highly specific CDK9 inhibitor with an IC50 value of 44±10 nM in vitro.

• CAS Number :

  [1073485-20-7]

• Product Name Alternative :

  LDC067

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis; CDK

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/LDC000067.html

• Purity :

  99.00

• Solubility :

  DMSO : ≥ 47 mg/mL

• Smiles :

  O=S(CC1=CC=CC(NC2=NC=NC(C3=CC=CC=C3OC)=C2)=C1)(N)=O

• Molecular Formula :

  C18H18N4O3S

• Molecular Weight :

  370.43

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Albert TK, et al. Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor. Br J Pharmacol. 2014 Jan;171 (1) :55-68.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDK1; CDK2; CDK4; CDK9