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Yhhu-3792

CAT: 0804-HY-120782-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-120782-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Yhhu-3792 is a Notch activator. Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs) . Yhhu-3792 promotes the expression of Hes3 and Hes5. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Thhu-3792 can be used for the treatment of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury[1][2].
CAS Number
2097826-24-7
UNSPSC
12352005
Target
Notch
Type
Reference compound
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/yhhu-3792.html
Purity
99.34
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
NC1=C2C(OC3=CC=CC(OC)=C3)=CC=CC2=NC(NC4=CC=C(C(C)C)C=C4)=N1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
References & Citations
[1]Lu H, et al. A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice. Stem Cells. 2018 Aug;36 (8) :1273-1285.|[2]Kunkanjanawan H, et al. Efficient large-scale expansion of cord blood-derived NK cells: leveraging lipopolysaccharide for enhanced NK cell production. Cytotherapy. 2025 Jun;27 (6) :782-789.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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