AMOZ

• Description :

  AMOZ is a carcinogenic metabolite of Furaltadone (HY-B1148A), which forms stable tissue residues by covalently binding to proteins as a hapten. AMOZ can be coupled with carrier proteins (such as BSA/OVA) to induce immune response and is released after acid hydrolysis. AMOZ residues can be detected by competitive ELISA method, and the detection limit in the monoclonal antibody 2E5.1 test is as low as 0.16 μg/kg (shrimp sample) . AMOZ can be used as a typical marker to monitor drug residues in animal-derived foods in the field of food safety[1][2].

• Product Name Alternative :

  3-Amino-5-morpholinomethyl-2-oxazolidone

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Antibiotic

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/amoz.html

• Concentration :

  10mM

• Purity :

  99.89

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1OC(CN2CCOCC2)CN1N

• Molecular Formula :

  C8H15N3O3

• Molecular Weight :

  201.23

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]UmapornPimpitak, et al. Development of a monoclonal antibody-based enzyme-linked immunosorbent assay for detection of the furaltadone metabolite, AMOZ, in fortified shrimp samples. Food Chemistry. Volume 116, Issue 3, 1 October 2009, Pages 785-791.|[2]Liu YC, et al. A novel chemiluminescent ELISA for detecting furaltadone metabolite, 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ) in fish, egg, honey and shrimp samples. J Immunol Methods. 2013 Sep 30;395 (1-2) :29-36.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [43056-63-9]