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CD8α mAb (2.43), InVivoPure+

CAT: 0013-GTR18521144-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18521144-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The CD8α mAb (2.43) reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. The CD8α mAb (2.43) is widely used as a phenotypic marker for mouse CD8 on cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR, including some NK cells and lymphoid dendritic cells
Product Name Alternative
Lyt 2.2, T-cell surface glycoprotein CD8 alpha chain, Cd8a, T-cell surface glycoprotein Lyt-2, lyt-2, lyt2, CD_antigen, CD8a, 2.43.1
UniProt
P01731
Reactivity
Mouse
Immunogen
Animals were immunized with CTL Clone L3 cells.
Target
CD8α
Clonality
Monoclonal
Clone
2.43
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Concentration
≥ 1 mg/ mL
Purity
≥ 95 % (CGE, reducing conditions) ≤ 5 % aggregates (analytical SEC) Endotoxin level ≤ 1 EU/mg
Form
Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Recomended Isotype: Rat IgG2b Isotype control, Recomended Isotype Catalog: orb3127216
Host or Source
Rat
Preservative
Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered
Isotype
Rat IgG2b k

UniProtKB · P01731

T-cell surface glycoprotein CD8 alpha chain

CD8A_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P01731
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cd8a
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

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sc-18860CD8 (2.43)
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