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EML734

CAT: 0804-HY-155814-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-155814-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EML734 is a potent and selective PRMT7/9 inhibitor with IC50 values of 315 nM and 0.89 μM, respectively.
CAS Number
3031795-11-3
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eml734.html
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C(N=CN2[C@@H]3O[C@H](CNC(NCCCNC(NC4=CC5=C(C=C(C=C5O)C(OC)=O)C=C4)=O)=N)[C@@H](O)[C@H]3O)C2=NC=N1
Molecular Formula
C27H32N10O7
Molecular Weight
608.61
References & Citations
[1]Alessandra Feoli, et al. Identification of a Protein Arginine Methyltransferase 7 (PRMT7) /Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor. J Med Chem. 2023 Aug 10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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