Riddelline

• Description :

  Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver[1].

• CAS Number :

  [23246-96-0]

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis

• Type :

  Natural Products

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/riddelline.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(/C(CC([C@]1(O)CO)=C)=C\C)O[C@@]2([H])[C@@]3([H])C(COC1=O)=CCN3CC2

• Molecular Formula :

  C18H23NO6

• Molecular Weight :

  349.38

• References & Citations :

  [1]J C Mirsalis, et al. In Vivo Measurement of Unscheduled DNA Synthesis and S-phase Synthesis as an Indicator of Hepatocarcinogenesis in Rodents. 5.097Q1 Cell Biol Toxicol. 1987 Jun;3 (2) :165-73.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported