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MES-SA/Dx-5

CAT: 0870-ABC-TC5562Size: 1 VialDry Ice: YesHazardous: No
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CAT#:0870-ABC-TC5562Size:1 Vial
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Description
The multi drug-resistant cell line MES-SA/Dx5 was derived from the human uterine sarcoma cell line MES-SA which was originally obtained from a tumour from a 56-year-old Caucasian female at the time of hysterectomy. The Dx5 variant exhibits a 100-fold resistance to Adriamycin and has a reported doubling time of 30 hours. The two additional marker chromosomes indicate clonal selection during drug selection. MES-SA/Dx-5 cells exhibit marked cross-resistance to a number of chemotherapeutic agents (including daunorubicin, dactinomycin, vincristine, taxol, colchicine) and moderate cross-resistance to MMC and melphalan.
Applications
For research use only
Storage Conditions
Liquid Nitrogen

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