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H357

CAT: 0870-ABC-TC5555Size: 1 VialDry Ice: YesHazardous: No
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CAT#:0870-ABC-TC5555Size:1 Vial
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Established from a squamous cell carcinoma (SCC) of the tongue (20mm) of a 74 year-old male patient. STNMP stage I, well differentiated, node negative tumour. Mutant p53, codon 110 exon 4, G to A; the previously reported mutant Ha-ras status of this cell line: codon: 13, G to A, codon 61, A-G is under investigation. This cell line is highly responsive to TGF (Transforming growth factor )-β and undergoes epithelial to mesenchymal transition. It expresses high levels of TGF-β1. Fahey et al (1996). Tumourigenic in athymic nude mice on subcutaneous injection and non-tumorigenic on orthotopic injection. Haplotype information: A*02,A*31; B*40,B*44; Cw*03,Cw*05
Applications
For research use only
Storage Conditions
Liquid Nitrogen

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