Pulchinenoside A

• Description :

  AA3 is a natural Pulsatilla saponin A that can improve synaptic plasticity in the hippocampus of adult mice and spatial memory in adult mice. It is also a non-competitive regulator of NMDA receptors.

• Product Name Alternative :

  Anemoside A3

• UNSPSC :

  12352005

• Target :

  IGluR

• Type :

  Natural Products

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/Pulchinenoside-A.html

• Purity :

  98.0

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  C[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@]([H])(O[C@@H]2[C@@H](O)[C@@H](O)CO[C@@]2([H])O[C@@H]3[C@](CO)(C)[C@]4([H])CC[C@@]5(C)[C@]6(C)CC[C@@]7(C(O)=O)CC[C@@H](C(C)=C)[C@]7([H])[C@@]6([H])CC[C@]5([H])[C@@]4(C)CC3)O1

• Molecular Formula :

  C41H66O12

• Molecular Weight :

  750.96

• References & Citations :

  [1]Ip FC et al. Anemoside A3 Enhances Cognition through the Regulation of Synaptic Function and Neuroprotection. Neuropsychopharmacology. 2015 Jul;40 (8) :1877-87.|[2]Zhang DM et al. Anemoside A3-induced relaxation in rat renal arteries: role of endothelium and Ca2+ channel inhibition. Planta Med. 2010 Nov;76 (16) :1814-9.|[3]Gao XD et al. Pulsatilloside A and anemoside A3 protect PC12 cells from apoptosis induced by sodium cyanide and glucose deprivation. Planta Med. 2003 Feb;69 (2) :171-4.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  NMDA Receptor

• CAS Number :

  [129724-84-1]