(S,R,S)-AHPC-PEG5-COOH

• Product Name Alternative:

  VH032-PEG5-COOH; VHL Ligand-Linker Conjugates 16; E3 Ligase Ligand-Linker Conjugates 58

• UNSPSC Description:

  (S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/vhl-ligand-linker-conjugates-16.html

• Purity:

  99.88

• Solubility:

  DMSO : 200 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL

• Smiles:

  O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCOCCOCCOCCOCCC(O)=O)=O)=O)C[C@H](O)C3

• Molecular Weight:

  750.90

• References & Citations:

  [1]Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  2172820-14-1