HSD17B13-IN-56-d3

HSD17B13-IN-56-d3

• CAS Number: 2770247-60-2
• UNSPSC Description: HSD17B13-IN-56-D3 (Compound 169) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-56-D3 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
• Target Antigen: 17β-HSD
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Solubility: 10 mM in DMSO
• Smiles: OC1=C(Cl)C=C(C(NC2=CC=C(C)C(N=C(C([2H])([2H])[2H])N3CC4=CC=CC=C4OC(F)(F)F)=C2C3=O)=O)C=C1Cl
• Molecular Weight: 555.35
• References & Citations: [1]Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported