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2,4-Dihydroxybenzaldehyde

CAT: 0804-HY-W007539-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W007539-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions[1][2].
CAS Number
95-01-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H402
Target
COX; Drug Intermediate; Endogenous Metabolite; NO Synthase; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-4-dihydroxybenzaldehyde.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=CC1=CC=C(O)C=C1O
Molecular Formula
C7H6O3
Molecular Weight
138.12
Precautions
H302, H315, H319, H335, H402
References & Citations
[1]Murtaza S, et al. Synthesis, biological activities and docking studies of novel 2, 4-dihydroxybenzaldehyde based Schiff base. Medicinal Chemistry Research, 2016, 25 (12) : 2860-2871.|[2]Jung H J, et al. Evaluation on pharmacological activities of 2, 4-dihydroxybenzaldehyde. Biomolecules & Therapeutics, 2009, 17 (3) : 263-269.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; Human Endogenous Metabolite; iNOS