JAK-IN-10

JAK-IN-10

• CAS Number: 916741-98-5
• UNSPSC Description: JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders[1]. JAK-IN-10 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: JAK
• Type: Reference compound
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/Benzenesulfonamide,_5-[[5-fluoro-4-[[4-_2-propyn-1-yloxy_phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-.html
• Purity: 99.72
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: O=S(C1=CC(NC2=NC=C(F)C(NC3=CC=C(OCC#C)C=C3)=N2)=CC=C1C)(N)=O
• Molecular Weight: 427.45
• References & Citations: [1]Hong Ren,et al. Composition for ophthalmic administration.US20140206708A1.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported