NucPE1

CAT: 0804-HY-101859-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-101859-01Size:5 mg
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Description
NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
CAS Number
[1404091-23-1]
Product Name Alternative
Nuc-H2O2 Probe
UNSPSC
12171500
Target
Reactive Oxygen Species (ROS)
Type
Dye Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/NucPE1.html
Purity
98.0
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1OC2(C3=C(OC4=C2C=CC(B5OC(C)(C)C(C)(C)O5)=C4)C=C(NCC)C(C)=C3)C6=C1C=CC=C6
Molecular Formula
C29H30BNO5
Molecular Weight
483.36
References & Citations
[1]Stanicka J, et al. NADPH oxidase-generated hydrogen peroxide induces DNA damage in mutant FLT3-expressing leukemia cells. J Biol Chem. 2015 Apr 10;290 (15) :9348-61.|[2]Dickinson BC, et al. A nuclear-localized fluorescent hydrogen peroxide probe for monitoring sirtuin-mediated oxidative stress responses in vivo. Chem Biol. 2011 Aug 26;18 (8) :943-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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