Phospho-BRAF (Ser446) Antibody

CAT: 0399-CSB-PA575128Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0399-CSB-PA575128Size:100 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Gene Aliases

FLJ95109 antibody; 94 kDa B raf protein antibody; B raf 1 antibody; B raf antibody; B Raf proto oncogene serine threonine protein kinase antibody; B Raf proto oncogene; serine/threonine kinase antibody; B RAF1 antibody; B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody; BRAF 1 antibody; BRAF antibody; BRAF_HUMAN antibody; BRAF1 antibody; cRmil antibody; MGC126806 antibody; MGC138284 antibody; Murine sarcoma viral (v-raf) oncogene homolog B1 antibody; Murine sarcoma viral v raf oncogene homolog B1 antibody; NS7 antibody; Oncogen BRAF antibody; oncogene BRAF1 antibody; p94 antibody; Proto-oncogene B-Raf antibody; Proto-oncogene c-Rmil antibody; RAFB 1 antibody; RAFB1 antibody; RMIL antibody; Serine/threonine-protein kinase B-raf antibody; v raf murine sarcoma viral oncogene homolog B antibody; v raf murine sarcoma viral oncogene homolog B1 antibody; v-Raf murine sarcoma viral oncogene homolog B1 antibody

UniProt

P15056

Host

Rabbit

Antigen Species

Human

Reactivity

Human, Mouse

Target Antigen

Peptide sequence around phosphorylation site of Serine 446 (R-D-S (p) -S-D) derived from Human B-RAF.

Target

BRAF

Clonality

Polyclonal

Conjugation

Non-conjugated

Field of Research

Cell Biology

Purification Method

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Form

Liquid

Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Type

Polyclonal Antibody

Tested Applications

ELISA, WB; WB:1:500-1:1000

Isotype

IgG

UniProtKB · P15056

Serine/threonine-protein kinase B-raf

BRAF_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P15056
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: BRAF
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.7.11.1
Processing: —
Secondary accessions: A4D1T4, B6HY61, B6HY62, B6HY63, B6HY64, B6HY65, B6HY66, Q13878, Q3MIN6, Q9UDP8, Q9Y6T3

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

Allosteric enzymeKinaseSerine/threonine-protein kinaseTransferase

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Disease

CardiomyopathyDeafnessDisease variantEctodermal dysplasiaIntellectual disabilityProto-oncogene

Cellular component

Cell membraneCytoplasmMembraneNucleus

Coding sequence diversity

Chromosomal rearrangement

Domain

Zinc-finger

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