PI3K p110γ Human Recombinant

• Description:

  PI3K p110γ Human Recombinant _x000D_ Catalog number: B2016849_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 20 µg_x000D_ Molecular Weight or Concentration: 130 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: p120-PI3K, Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit γ isoform, PI3K-γ, PI3-kinase Subunit γ_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Raynaud FI, Eccles S, Clarke PA, Hayes A, Nutley B, Alix S, Henley A, Di-Stefano F, Ahmad Z, Guillard S, Bjerke LM, Kelland L, Valenti M, Patterson L, Gowan S, de Haven Brandon A, Hayakawa M, Kaizawa H, Koizumi T, Ohishi T, Patel S, Saghir N, Parker P, Waterfield M, Workman P. Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases Cancer Res. 2007 Jun 15;67(12):5840-50._x000D_ 2: Bonnans C, Fukunaga K, Keledjian R, Petasis NA, Levy BD. Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury J Exp Med. 2006 Apr 17;203(4):857-63._x000D_ 3: Edling CE, Selvaggi F, Buus R, Maffucci T, Di Sebastiano P, Friess H, Innocenti P, Kocher HM, Falasca M. Key role of phosphoinositide 3-kinase class IB in pancreatic cancer Clin Cancer Res. 2010 Oct 15;16(20):4928-37._x000D_ 4: Vinnikov IA, Hajdukiewicz K, Reymann J, Beneke J, Czajkowski R, Roth LC, Novak M, Roller A, Dörner N, Starkuviene V, Theis FJ, Erfle H, Schütz G, Grinevich V, Konopka W. Hypothalamic miR-103 protects from hyperphagic obesity in mice J Neurosci. 2014 Aug 6;34(32):10659-74._x000D_ 5: Boulven I, Levasseur S, Marois S, Paré G, Rollet-Labelle E, Naccache PH. Class IA phosphatidylinositide 3-kinases, rather than p110 gamma, regulate formyl-methionyl-leucyl-phenylalanine-stimulated chemotaxis and superoxide production in differentiated neutrophil-like PLB-985 cells J Immunol. 2006 Jun 15;176(12):7621-7._x000D_ 6: Metjian A, Roll RL, Ma AD, Abrams CS. Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus J Biol Chem. 1999 Sep 24;274(39):27943-7._x000D_ 7: Lu Z, Jiang YP, Ballou LM, Cohen IS, Lin RZ. Galpha q inhibits cardiac L-type Ca2+ channels through phosphatidylinositol 3-kinase J Biol Chem. 2005 Dec 2;280(48):40347-54._x000D_ 8: Voigt P, Dorner MB, Schaefer M. Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B J Biol Chem. 2006 Apr 14;281(15):9977-86._x000D_ 9: Voigt P, Brock C, Nürnberg B, Schaefer M. Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma J Biol Chem. 2005 Feb 11;280(6):5121-7._x000D_ 10: Aytenfisu TY, Campbell HM, Chakrabarti M, Amzel LM, Gabelli SB. Class I PI3K Biology Curr Top Microbiol Immunol. 2022;436:3-49. _x000D_ _x000D_ Products Related to PI3K p110γ Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2016849 (20 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3