Taranabant

CAT: 0804-HY-10013-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-10013-01Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro.

CAS Number

701977-09-5

Product Name Alternative

MK-0364

UNSPSC

12352005

Hazard Statement

H372, H400

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Taranabant.html

Purity

99.14

Solubility

DMSO : ≥ 42 mg/mL

Smiles

ClC1=CC=C(C[C@@H](C2=CC=CC(C#N)=C2)[C@@H](NC(C(C)(OC3=CC=C(C=N3)C(F)(F)F)C)=O)C)C=C1

Molecular Formula

C27H25ClF3N3O2

Molecular Weight

515.95

Precautions

H372, H400

References & Citations

[1]Fong TM, et al. Antiobesity Efficacy of a Novel Cannabinoid-1 Receptor Inverse Agonist, N-[ (1S,2S) -3- (4-Chlorophenyl) -2- (3-cyanophenyl) -1-methylpropyl]-2 -methyl-2-{[5- (trifluoromethyl) pyridin-2-yl]oxy}propanamide (MK-0364), in Rodents. J Pharmacol Exp T|[2]Lin LS, et al. Discovery of N-[ (1S,2S) -3- (4-Chlorophenyl) -2- (3-cyanophenyl) -1-methylpropyl]-2-methyl-2- {[5- (trifluoromethyl) pyridin-2-yl]oxy}propanamide (MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity. J M

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Alternative Products

Catalog	Name
A3858-2	Taranabant
BDB97700-01	Taranabant racemate
A11578-50	Taranabant 50mg
A11578-25	Taranabant 25mg
A11578-1	Taranabant 1mg
A11578-10	Taranabant 10mg
A11578-5	Taranabant 5mg
A11578-2	Taranabant 2mg
A21699-50	Taranabant racemate 50mg
A21699-5	Taranabant racemate 5mg

Taranabant

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