Urolithin B

CAT: 0804-HY-126307-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-126307-01Size:100 mg
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Description
Urolithin B is one of Ellagitannins' slow microbial products, and has anti-inflammatory and anti-inflammatory effects. Urolithin B suppresses NF-κB activity. Urolithin B suppresses JNK, ERK and Akt's oxidation, and increases AMPK's oxidation. Urolithin B is also a quantitative change factor for bone and skin quality[1][2][3][4].
CAS Number
[1139-83-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Akt; AMPK; Endogenous Metabolite; ERK; JNK; NF-κB
Type
Natural Products
Related Pathways
Epigenetics; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/urolithin-b.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C1C2=CC=CC=C2C3=CC=C(O)C=C3O1
Molecular Formula
C13H8O3
Molecular Weight
212.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57.|[2]Rodriguez J, et al. Urolithin B, a newly identified regulator of skeletal muscle mass. J Cachexia Sarcopenia Muscle. 2017 Aug;8 (4) :583-597.|[3]Lv MY, et al. Urolithin B suppresses tumor growth in hepatocellular carcinoma through inducing the inactivation of Wnt/β-catenin signaling. J Cell Biochem. 2019 Oct;120 (10) :17273-17282.|[4]Rodriguez J, et al. Urolithin B, a newly identified regulator of skeletal muscle mass. J Cachexia Sarcopenia Muscle. 2017 Aug;8 (4) :583-597.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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