Phe-Lys(Fmoc)-PAB

• UNSPSC Description:

  Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/phe-lys-fmoc-pab.html

• Purity:

  99.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OCC(C=C1)=CC=C1NC([C@@H](NC([C@@H](N)CC2=CC=CC=C2)=O)CCCCNC(OCC3C4=CC=CC=C4C5=CC=CC=C35)=O)=O

• Molecular Weight:

  620.74

• References & Citations:

  [1]Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2149584-03-0