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Cefaloglycin

CAT: 0804-HY-16137-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-16137-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration[1][2][3].
CAS Number
3577-01-3
Product Name Alternative
Cephaloglycin
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cefaloglycin.html
Purity
96.06
Solubility
10 mM in DMSO
Smiles
OC(C(N(C1=O)[C@@](SC2)([H])[C@@H]1NC([C@@H](C3=CC=CC=C3)N)=O)=C2COC(C)=O)=O
Molecular Formula
C18H19N3O6S
Molecular Weight
405.42
Precautions
H302, H312, H332
References & Citations
[1]B M Tune, et al. The Renal Mitochondrial Toxicity of Beta-Lactam Antibiotics: In Vitro Effects of Cephaloglycin and Imipenem. J Am Soc Nephrol. 1990 Nov;1 (5) :815-21.|[2]S Shadomy, et al. In Vitro Activities of Five Oral Cephalosporins Against Aerobic Pathogenic Bacteria. Antimicrob Agents Chemother. 1977 Nov;12 (5) :609-13.|[3]E Bergogne-Bérézin. Continuous Activity of Significant Antibiotics. Clin Ther. Jan-Feb 1991;13 (1) :181-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched

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