Cefaloglycin

• Description :

  Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration[1][2][3].

• CAS Number :

  [3577-01-3]

• Product Name Alternative :

  Cephaloglycin

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H312, H332

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/cefaloglycin.html

• Purity :

  96.06

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C(N(C1=O)[C@@](SC2)([H])[C@@H]1NC([C@@H](C3=CC=CC=C3)N)=O)=C2COC(C)=O)=O

• Molecular Formula :

  C18H19N3O6S

• Molecular Weight :

  405.42

• Precautions :

  H302, H312, H332

• References & Citations :

  [1]B M Tune, et al. The Renal Mitochondrial Toxicity of Beta-Lactam Antibiotics: In Vitro Effects of Cephaloglycin and Imipenem. J Am Soc Nephrol. 1990 Nov;1 (5) :815-21.|[2]S Shadomy, et al. In Vitro Activities of Five Oral Cephalosporins Against Aerobic Pathogenic Bacteria. Antimicrob Agents Chemother. 1977 Nov;12 (5) :609-13.|[3]E Bergogne-Bérézin. Continuous Activity of Significant Antibiotics. Clin Ther. Jan-Feb 1991;13 (1) :181-8.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched