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Gremubamab

CAT: 0804-HY-P99649-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99649-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gremubamab (MEDI3902) is a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody. Gremubamab binds to the PA PcrV protein and Psl exopolysaccharide. Gremubamab has the potential for the research of pseudomonas aeruginosa infections[1][2].
CAS Number
1800381-36-5
Product Name Alternative
MEDI3902
UNSPSC
12352203
Target
Bacterial
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gremubamab.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
[Gremubamab]
Molecular Weight
(200.46 kDa)
References & Citations
[1]Chastre J, et al. Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial. Crit Care. 2022 Nov 15;26 (1) :355. |[2]Le HN, et al. Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models. Antimicrob Agents Chemother. 2019 Jul 25;63 (8) :e00710-19.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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