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INCB059872

CAT: 0804-HY-141677-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141677-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
INCB059872 is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor. INCB059872 can be used for the research of myeloid leukemia[1].
CAS Number
1802909-49-4
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/incb059872.html
Purity
98.06
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC(C1(CCC1)CN2CCC(COC)(CC2)CN[C@H]3[C@@](C4=CC=CC=C4)([H])C3)=O
Molecular Formula
C23H34N2O3
Molecular Weight
386.53
References & Citations
[1] Johnston G, et al. Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia. Gene. 2020;752:144758.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
KDM1/LSD1

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