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Olopatadine

CAT: 0804-HY-W062109Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W062109Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[1][2].
CAS Number
113806-05-6
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Endogenous Metabolite; Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/olopatadine.html
Purity
98.94
Solubility
10 mM in DMSO
Smiles
O=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C\CCN(C)C
Molecular Formula
C21H23NO3
Molecular Weight
337.41
Precautions
H302, H312, H332
References & Citations
[1]Kam KW, et al. Topical Olopatadine in the Treatment of Allergic Conjunctivitis: A Systematic Review and Meta-analysis. Ocul Immunol Inflamm. 2017 Oct;25 (5) :663-677.|[2]Leonardi A, et al. Olopatadine: a drug for allergic conjunctivitis targeting the mast cell. Expert Opin Pharmacother. 2010 Apr;11 (6) :969-81.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor

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