(S,R,S)-AHPC-Me-C10-NH2

(S,R,S)-AHPC-Me-C10-NH2

• CAS Number: 2376139-52-3
• UNSPSC Description: (S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-me-c10-nh2.html
• Purity: 96.19
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@@H](NC(CCCCCCCCCCN)=O)C(C)(C)C)=O
• Molecular Weight: 627.88
• References & Citations: [1]Wei J, et al. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader. J Med Chem. 2019 Dec 12;62(23):10897-10911.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported